Scientist Antibody Discovery Job at Global Channel Management, Inc, South San Francisco, CA

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  • Global Channel Management, Inc
  • South San Francisco, CA

Job Description

Scientist Antibody Discovery needs significant experience in antibody discovery and protein engineering by using single B cell cloning hybridoma or phage/yeast display techniques

Scientist Antibody Discovery requires:

PhD in Biochemistry Biomedical/Chemical Engineering Immunology or related field with minimum of 2 years of postgraduate experience (preferably in industry) MS with 8 years of research experience BS with 10 years of research experience in antibody or protein engineering

Strong background in molecular biology antibody and protein expression and biophysical characterization of recombinant antibodies and proteins

Demonstrated experience in working collaboratively across various scientific disciplines and other parts of the organization to meet end goals

Highly motivated individual with exceptionally good organizational skills and attention to details

Experience in single domain antibodies multispecific antibody engineering Fc engineering antibody drug conjugates nave phage or yeast display library design

Experience in NGS analysis for antibody discovery and engineering

Significant contributions to successful biologics drug discovery programs in biotech/biopharma industry

Scientist Antibody Discovery duties:

Design strategies and execute antibody discovery campaigns for therapeutic and reagent antibodies using phage display

Generate antibody fragment libraries for antibody discovery and engineering perform HT binding screens (ELISA and multiplex flow cytometry) and sequence analysis to generate hits

Rankorder clones by affinity in vitro potency and early developability assessment

Execute sequence optimization of lead antibodies to improve developability and binding affinity

Remote Work :

No

Job Tags

Remote job,

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